Callie and George get back from Las Vegas, announcing their marriage, much to everyone's disbelief. Izzie is disappointed in what she invested Denny's legacy in, and tries to steal patients from the emergency room. The Denny Duquette Memorial Clinic is open for business, but only one single patient shows up. The race for the Chief's position is on, and the attending physicians, Derek, Burke, Addison and Mark, compete for Richard's affections by trying to help out everywhere possible. Richard endeavors to reunite with his wife, Adele, and decides to retire, only to come home and find his wife with another man. Cristina and Burke still don't speak to each other, but he breaks the agreement when he proposes to her. George, devastated after his father's death, uses sex to overcome his grief, and eventually proposes to Callie. He also displays his lack of support in Bailey's plan to create a free medical clinic, but she ultimately goes through with her plan when Izzie offers to spend her entire 8.7 million dollar inheritance on the project. The attending physicians at Seattle Grace Hospital fight to get Richard's attention, but he expresses his disappointment. Derek is angry at Meredith for causing Mark to stay in Seattle, but soon realizes that she is not the reason he is really angry. Mark is determined to leave Seattle for good but Meredith accidentally has him stay after letting him know of the open Chief position. After the Chief announces his retirement, rumors begin to circulate on his departure and successor. This is closest thing to joining a full time medical course that will cost you over thousands of dollars. The secret is in following proven lessons, mastering the subject one step at a time - At your own speed with detailed illustrations. You see, once an expert explains to you how to actually do it.in language you can easily understand.this is almost as easy as.eating lunch.

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